Clinical Case Database / Category: Patient Management

A classic case of toxoplasma retinitis

Publication details

Mrs Meyyammai Mohan, Mr Mohamed Alarbi, Dr Anuragini Karthikeyan
Foundation Years Journal, volume 9, issue 6, p.36 (123Doc Education, London, June 2015)


We present a classic case of toxoplasmosis retinitis in a 44 year old male, highlighting key aspects of diagnosis and management to help guide clinical practice. Diagnosis is largely clinical so key signs have been explained, and the rationale for the chosen treatment plan, including acceptable alternatives, are also explored. Important differentials, especially in the immunocompromised population, are also discussed and important means of differential testing are addressed. We discuss current knowledge on this subject, summarise key points and present multiple-choice questions for self-testing.

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Mrs Meyyammai Mohan

Consultant Ophthalmology
Burnley General Hospital, Casterton Avenue
Burnley, Lancashire, BB10 2PQ

Mr Mohamed Alarbi

Associate Specialist, Ophthalmology
Burnley General Hospital, Casterton Avenue
Burnley, Lancashire, BB10 2PQ

Dr Anuragini Karthikeyan (Corresponding author)

Clinical Fellow, Ophthalmology
Burnley General Hospital, Casterton Avenue
Burnley, Lancashire, BB10 2PQ


1. Atmaca LS, Simsek T, Batioglu F. Clinical features and prognosis in ocular toxoplasmosis. Jpn J Ophthalmol. 2004;48:386–391.
2. Bodaghi, B., et al. "Toxoplasmosis: new challenges for an old disease." Eye 26.2 (2012): 241-244.
3. Kanski, Jack J., and Brad Bowling. Clinical ophthalmology: a systematic approach. Elsevier Health Sciences, 2011.


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About the Clinical Cases Database

T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

The database is fully searchable, or can be browsed by medical specialty. Abstracts can be read free of charge, however a subscription is required in order to read the complete cases.