Clinical Case Database / Category: Patient Management

A difficult case of Crohn's disease: assessment and management

Publication details

K Siau, G Townson
Foundation Years Journal, volume 9, issue 2, p.6 (123Doc Education, London, February 2015)


Crohn's disease (CD) is a chronic inflammatory disease affecting the gastrointestinal tract. The disease is relatively common, and may be encountered by junior doctors working in various specialties. Assessment of disease and patient management may be challenging. Here, we describe a young patient with a new diagnosis of CD following an acute medical admission, and discuss his outpatient journey.

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K Siau

Gastroenterology SpR, University Hospital Birmingham,
Mindelsohn Way, Birmingham, B15 2TH.

G Townson (Corresponding author)

Consultant Gastroenterologist, Princess Royal Telford,
Grainger Drive, Telford, TF1 6TF.


1. Baumgart DC and Sandborn WJ, Crohn's Disease, Lancet 2012; 380 (9853), 1590-1605
2. First principles of Gastroenterology – the basis of disease and approach to treatment: Inflammatory Bowel Disease.
3. Chande N, et al. Azathioprine or 6-mercaptopurine for induction of remission in Crohn's disease, Cochrane Database Syst Rev. 2013 Apr 30;4:CD000545.doi:10.1002/14651858.CD000545.pub4.
4. NACC Patient Information Leaflet on Azathioprine and 6-MP: and Mercaptopurine.pdf
5. American College of Gastroenterology guideline - Management of Crohn's Disease in Adults:'s-disease-in-adults/
6. Lim WC, Hanauer S, Aminosalicylates for induction of remission or response in Crohn's disease, Cochrane Database Syst Rev. 2010 Dec 8;(12):CD008870
7. Da W et al, Adalimumab for Crohn's disease after infliximab treatment failure: a systematic review, Eur J Gastroenterol Hepatol, 2013 Aug;25(8):885-91


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T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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