Clinical Case Database / Category: Clinical Care

A patient admitted following an overdose of paracetamol

Publication details

Dr Lucy Norman, Dr Coral Lever
Foundation Years Journal, volume 4, issue 5, p.28 (123Doc Education, London, May 2010)

Abstract

A 19-year-old girl presented to the A&E department at 10.30am after having taken an overdose of 16g paracetamol at 8am that morning. There was no prior history of alcohol excess or recreational drug intake. She denied suicidal intent and was upset that she had taken the overdose, claiming that she would not attempt the overdose again. On examination she was tearful, but no abnormalities could be detected.

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Authors

Dr Lucy Norman

Foundation Year 1
Southampton University Hospitals NHS Trust

Dr Coral Lever

Specialist Registrar in Gastroenterology
Southampton University Hospitals NHS Trust

References

1.  Ramrkha P, Moore M (2005) Oxford Handbook of Acute Medicine, 2nd edition. Oxford University Press, pp. 828–831.

2.  Polson J, Lee WM (2005) AASLD Position Paper: The Management Of Acute Liver Failure. Hepatology, May;41(5).

3.  www.ars-informatica.ca/content/acetaminophen1.gif

4.  Wolf SJ, Heard K, Sloan EP, Jagoda AS (2007) Clinical Policy: Critical Issues in the Management of Patients Presenting to the Emergency Department With Acetaminophen Overdose. Annals of Emergency Medicine, September;50(3).

5.  Devlin J, O’Grady J (2000) Indications for referral and assessment in adult liver transplantation: a clinical guideline. BSG Guidelines in Gastroenterology, February.

5.  Kumar P, Clark ML (2002) Clinical Medicine, 5th edition. Saunders.

6.  Mulcahy HE, Hegarty HE. Paracetamol Hepatotoxicty. Gastroenterology and Liver Unit, St.Vincent’s Hospital, Elm Park, Dublin 4.

7.  Brok J, Buckley N, Gluud C (2009) Interventions for paracetamol (acetaminophen) overdose (Review). The Cochrane Collaboration, Issue 3. The Cochrane library. Wiley Publishers.

8.  Prescott LF (2000) Paracetamol, alcohol and the liver. British Journal Clinical Pharmacology, 49(4):291–30.

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About the Clinical Cases Database

T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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