Clinical Case Database / Category: Patient Management

Amiodarone and the thyroid

Publication details

Kelly Cheer MBChB, MRCP, Sushnita Pearce BMedSci, BMBS, FRCP
Foundation Years Journal, volume 4, issue 9, p.39 (123Doc Education, London, December 2010)

Abstract

Amiodarone is a highly effective and frequently used treatment for cardiac arrhythmias. This article reviews the effects of amiodarone on the thyroid, and discusses the diagnosis and treatment of amiodarone-induced thyroid dysfunction.

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Authors

Kelly Cheer MBChB, MRCP

Specialty Registrar in Diabetes and Endocrinology

Sushnita Pearce BMedSci, BMBS, FRCP

Consultant in Diabetes and Endocrinology

References

1. Kennedy L, Basu A (2007) Problem Solving in Endocrinology & Metabolism. Amiodarone and the thyroid. Clinical Publishing, 21–26.
2. Cohen-Lehman J, Dahl P, Danzi S, Klein I (2010) Effects of amiodarone therapy on thyroid function. Nat Rev Endocrinol, 6: 34–41
3.Raebel MA, Carroll NM, Simon SR, Andrade SE, Feldstein AC, Lafata JE et al. (2006) Liver and thyroid monitoring in ambulatory patients prescribed amiodarone in 10 HMOs. J Manag Care Pharm, 12(8): 656–664.
4. Newman CM, Price A, Davies DW, Gray TA, Weetman AP (1998) Amiodarone and the thyroid: a practical guide to the management of thyroid dysfunction induced by amiodarone therapy. Heart, 79: 121–127.
5. Eskes SA & Weirsinga WM (2009) Amiodarone and the thyroid. Best Practice and Research Clinical Endocrinology and Metabolism, 23: 735–751.
6. Cooper DS (2005) Antithyroid Drugs. New Engl J Med, 352: 905–917.

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Conflict Of Interest

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About the Clinical Cases Database

T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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