Clinical Case Database / Category: Clinical Care

Anaphylaxis and venom immunotherapy

Publication details

Dr Elizabeth Waldegrave, MBBS, Dr Jessica Gale, MBChB, Professor Helen Chapel, MD, FRCPath, FRCP
Foundation Years Journal, volume 5, issue 2, p.46 (123Doc Education, London, March 2011)


We describe the case of a patient who had an anaphylactic reaction to a wasp sting and elicit the typical features of anaphylaxis. We go onto discuss the underlying immunology looking specifically at the role of IgE. We review appropriate emergency management, and subsequent investigation of anaphylaxis. Finally, the role of venom immunotherapy is explored.

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Dr Elizabeth Waldegrave, MBBS

Rheumatology FY2
Wycombe General Hospital
Buckinghamshire Hospitals Trust

Dr Jessica Gale, MBChB

Accident & Emergency F2
Wycombe General Hospital,
Buckinghamshire Hospitals Trust

Professor Helen Chapel, MD, FRCPath, FRCP

Consultant Immunologist
Nuffield Department of Medicine
University of Oxford and Oxford Radcliffe Hospitals NHS Trust


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T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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