Clinical Case Database / Category: Patient Management
Cerebral toxoplasmosis
Publication details
Dr Adam McCulloch MBChB, Dr David Rowen
Foundation Years Journal, volume 4, issue 3, p.12 (123Doc Education, London, March 2010)
Abstract
Collapse of unknown cause is a presenting symptom often encountered by junior doctors on the medical assessment unit. This presentation generates a number of possible diagnoses. One of the potential diagnoses is cerebral toxoplasmosis, the most common opportunistic infection of the central nervous system in HIV positive patients. The case of Ms TW will be presented which illustrates the initial difficulties in diagnosis, the chosen treatment regimen, follow-up and length of treatment.
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Authors
Dr Adam McCulloch MBChB
Foundation Year 2 Doctor (Cardiology)
a_max15@hotmail.com
Dr David Rowen
Consultant
Genitourinary Medicine
Southampton University Hospital Trust
david.rowen@scpct.nhs.uk
References
1. Nicoll JR (2006) Viral and other Infections. In: D Graham, A Nicoll, I Bone. Introduction to Neuropathology, 3rd edn. London: Hodder Headline Group, 149–150.
2. Goorney B (2009) Genito-urinary medicine and AIDS. In PA Kalra, Essential Revision Notes for MRCP, 3rd edn. Cheshire: Pastest Ltd, 204–205.
3. Porter S, Sande M (1992) Toxoplasmosis of the central nervous system in the acquired immunodeficiency syndrome. N Eng J Med, 327:1643–1648.
4. Brew BJ (2001) Toxoplasmosis. In: BJ Brew, HIV Neurology. New York: Oxford University Press, 117–123.
5. Portegies P, Solod L, Cinque P, et. al. (2004) Guidelines for the diagnosis and management of neurological complications of HIV infection. Eur J Neur, 11:297–304.
6. Sukthana Y (2006) Toxoplasmosis: beyond animals to humans. Trends in Parasitology, 22:246.
7. BMJ Case Reports. Multiple ring enhancing lesions in brain MRI of a patient with AIDS http://casereports.bmj.com/cgi/content/full/2009/feb16_1/bcr2006108282
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About the Clinical Cases Database
The Foundation Years Clinical Cases Database is a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.
The database is fully searchable, or can be browsed by medical specialty. Abstracts can be read free of charge, however a subscription is required in order to read the complete cases.