Clinical Case Database / Category: Patient Management

Chronic kidney disease - mineral bone disease

Publication details

Matthew Graham-Brown, David Bennett-Jones, Mohamed Thahir
Foundation Years Journal, volume 5, issue 2, p.9 (123Doc Education, London, March 2011)


A 59-year old female, with end-stage renal failure (ESRF) secondary topolycystic kidney disease (APKD) on continuous ambulatory peritoneal dialysis (CAPD), was seen as part of a routine follow-up in outpatients.She complained of tingling around her mouth, as well as numbness andtingling in her fingers. She had been diagnosed with APKD in 1987 and had had 18 months of CAPD before a deceased donor renal transplant in 1992 which failed after 15 years, necessitating her return to CAPD. Her medication consisted of an ACE-inhibitor, a calcium channel blocker, levothyroxine,an active vitamin D analogue and a calcium containing phosphate binder. Her only other medical conditions were hypertension, hypothyroidism andprevious partial parathyroidectomy.

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Matthew Graham-Brown

FY1 – University hospital Coventry and Warwickshire

David Bennett-Jones

Consultant Renal Physician
University hospital Coventry and Warwickshire

Mohamed Thahir

Specialist Registrar Medicine
University hospital Coventry and Warwickshire


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About the Clinical Cases Database

T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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