Clinical Case Database / Category: Case Based Discussion

Diabetic ketoacidosis: diagnosis and management in adults

Publication details

Dr A Theodoraki, Dr SE Baldeweg
Foundation Years Journal, volume 2, issue 7, p.309 (123Doc Education, London, September 2008)

Abstract

A 25-year-old man presents to the Emergency department with a 2-week history of polyuria and polydipsia and a 2-day history of vomiting and abdominal pain. In the past fortnight he has also noticed some weight loss and progressive generalised weakness. He has been fit and healthy and is not on any regular medication.

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Authors

Dr A Theodoraki

Specialist Registrar in Diabetes and Endocrinology
North Thames Central London Rotation

Dr SE Baldeweg (Corresponding author)

Consultant Physician in Diabetes and Endocrinology
Department of Endocrinology
University College
London Hospitals
London NW1 2BU

References

1. Alberti KG, Zimmer PZ. Definition, diagnosis and classification of DM and its complications. Part1: diagnosis and classification of DM. Provisional report of a WHO consultation. Diabetic Medicine, 1998, 15:539–553.
2. Savage MW, Kilbert A. On behalf of the Association of British Clinical Diabetologists (ABCD).ABCD guidelines for the management of hyperglycaemic emergencies in adults. Practical Diabetes International, 2006, Vol 23 (5): 227–231.
3. Kitabchi AE, Wall B. Diabetes care update: Management of diabetic ketoacidosis. American family phycisian, 1999, vol 60 (2):455–464.
4. Walace TM, Matthews DR. Recent advances in the monitoring and management of diabetic ketoacidosis. Q J Med, 2004, 97:773–780.
5. American Diabetes Association. Hyperglycemic crisis in diabetes. Diabetes Care, 2004, 27 (1):S94–S102.
6. Umpierez GE, Smiley G, Kitabchi A. Narrative review: Ketosis- prone type 2 Diabetes Mellitus. Ann Intern Med, 2006, 144:350–357.
7. Brandenbeurg MA, Dire DJ. Comparison of arterial and venous blood gas values in the initial emergency department evaluation of patients with diabetic ketoacidosis. Ann Emerg Med, 1998, 31:459–465.
8. Dunger DB, Sperling MA et al. ESPE/ LWPES consensus statement on diabetes ketoacidosis in children and adolescents. Arch Dis Child, 2004, 89:188–194.
9. Nice Institute for Clinical Excellence. Type 1 diabetes: Diagnosis and management of type 1 diabetes in children, young people and adults. Clinical guideline, 15, July 2004.

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About the Clinical Cases Database

T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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