Clinical Case Database / Category: Case Based Discussion

Early pregnancy with right frontal lobe oligodendroglioma

Publication details

Dr S Parameshwaran, MBBS, MRCOG, Dr L Kean, BMBCh, DM, FRCOG
Foundation Years Journal, volume 8, issue 7, p.32 (123Doc Education, London, July 2014)


Hyperemesis Gravidarum (HG) is characterized by intractable nausea, vomiting and dehydration and affects about 0.5-2% of pregnant women. HG is considered a rare complication of pregnancy, but because nausea and vomiting during pregnancy exist on a spectrum, it is often difficult to distinguish this condition from the more common form of nausea and vomiting experienced during pregnancy known as morning sickness. HG tends to start in the first trimester of pregnancy and last significantly longer than morning sickness. While most women will experience near-complete relief of morning sickness symptoms near the beginning of their second trimester, some sufferers of HG will experience severe symptoms until they give birth to their baby, and sometimes even after giving birth. A Foundation doctor working in Obstetrics and Gynaecology will definitely encounter women with HG. It is important to bear in mind other diagnoses which may present with similar symptoms.

Access the Clinical Cases Database

A subscription is required to read the full article. Please subscribe using one of the options below.

Foundation Years Clinical Cases Database£29.006 months
Add to cart
Foundation Years Clinical Cases Database£39.0012 months
Add to cart


Dr S Parameshwaran, MBBS, MRCOG

Nottingham University Hospitals NHS Trust
City Campus, Nottingham, NG5 1PB


Nottingham University Hospitals NHS Trust
City Campus, Nottingham, NG5 1PB


1. Mork SJ, Lindegaard KF, Halvorsen TB, et al. Oligodendroglioma: incidence and biological behavior in a defined population. J Neurosurg 1985;63:881-9. [PUBMED]
2. Rubinstein LJ. Tumors of the central nervous system. In: Armed forces Institute of Pathology: Atlas of tumor pathology, series 2, fascicle 6. Bethesda 1972:85-104.
3. Chin HW, Hazel JJ, Kim TH, Webster JH. Oligodendrogliomas. A review of two hundred cases. Cancer 1980;45:1458-66. [PUBMED]
4. Osborn AG. Diagnostic Neuroradiology. Mosby, St Louis, Missouri 1994;564-5.
5. Lee YY, Van Tassel P. Intracranial oligodendrogliomas: imaging findings in 35 untreated cases. AJR Am J Roentgenol 1989;152:361-9.
6. Herbert H.Engelhard,Ana Stelea Oligodendroglioma and Anaplastic Oligodendroglioma:Clinical features Treatment and Prognosis Surgical Neurol 2003;60:443-56


Conflict Of Interest

The Journal requires that authors disclose any potential conflict of interest that they may have. This is clearly stated in the Journal’s published “Guidelines for Authors”. The Journal follows the Guidelines against Conflict of Interest published in the Uniform Requirements for Manuscripts Submitted to Biomedical Journals (

Financial Statement

The authors of this article have not been paid. The Journal is financed by subscriptions and advertising. The Journal does not receive money from any other sources. The decision to accept or refuse this article for publication was free from financial considerations and was solely the responsibility of the Editorial Panel and Editor-in-Chief.

Patient Consent statement

All pictures and investigations shown in this article are shown with the patients’ consent. We require Authors to maintain patients’ anonymity and to obtain consent to report investigations and pictures involving human subjects when anonymity may be compromised. The Journal follows the Guidelines of the Uniform Requirements for Manuscripts ( The Journal requires in its Guidelines for Authors a statement from Authors that “the subject gave informed consent”.

Animal & Human Rights

When reporting experiments on human subjects, the Journal requires authors to indicate whether the procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the HelsinkiDeclaration of 1975, as revised in 2008.

About the Clinical Cases Database

T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

The database is fully searchable, or can be browsed by medical specialty. Abstracts can be read free of charge, however a subscription is required in order to read the complete cases.