Clinical Case Database / Category: Patient Management

Food induced idiopathic hypertension and oedema

Publication details

Dr Shideh Pouria MB, BS BSc, MRCP (UK), PhD, Dr John R Mansfield MRCS, LRCP, DRCOG
Foundation Years Journal, volume 7, issue 8, p.10 (123Doc Education, London, August 2013)


We present a case of food induced intractable idiopathic hypertension and oedema, responding to an exclusion diet followed by provocation of symptoms on reintroducing the excluded foods. The patient was subsequently treated with intradermal, low dose, antigen-specific immunotherapy to the identified foods which allowed controlling both blood pressure and oedema despite withdrawal of all pharmacological therapies. The possible role of food intolerance in the development of hypertension and oedema and its treatment are discussed.

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Dr Shideh Pouria MB, BS BSc, MRCP (UK), PhD

Medical Director Burghwood Clinic
Visiting Research Fellow Nutritional Sciences Division
School of Medicine
King’s College London

Dr John R Mansfield MRCS, LRCP, DRCOG

General Practitioner at Burghwood Clinic


1. Miller, JB. Food Allergy: Provocative Testing and Injection Therapy; Thomas publications 1972.
2. Grant, EC. Food Allergies and Migraine. Lancet 1979: 1(8123):966-9.
3. Rea, W.J. Chemical Sensitivity 1995 Vol 3 CRC Publishing.


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T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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