Clinical Case Database / Category: Clinical Care
Infective endocarditis: how immunology tests may help or mislead
John Maher MRCPI MRCP MSc PhD FRCPath
Foundation Years Journal, volume 5, issue 2, p.57 (123Doc Education, London, March 2011)
Immunopathology plays an important role in infective endocarditis. In this context, two cases are presented here. In both patients, several abnormal immunological test results were obtained. Some findings were typical, whereas others were unanticipated and potentially misleading. Failure to interpret such findings correctly could lead to selection of inappropriate and potentially highly dangerous treatment. Pitfalls associated with immunological testing in this model of chronic infection are discussed. The need for clinicopathological liaison in the interpretation of diagnostic results is emphasized.
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John Maher MRCPI MRCP MSc PhD FRCPath
Senior Lecturer in Immunology
Allergy & Clinical Immunology
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