Clinical Case Database / Category: Clinical Care

Infective endocarditis: how immunology tests may help or mislead

Publication details

Foundation Years Journal, volume 5, issue 2, p.57 (123Doc Education, London, March 2011)


Immunopathology plays an important role in infective endocarditis. In this context, two cases are presented here. In both patients, several abnormal immunological test results were obtained. Some findings were typical, whereas others were unanticipated and potentially misleading. Failure to interpret such findings correctly could lead to selection of inappropriate and potentially highly dangerous treatment. Pitfalls associated with immunological testing in this model of chronic infection are discussed. The need for clinicopathological liaison in the interpretation of diagnostic results is emphasized.

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Senior Lecturer in Immunology
Research Oncology
Hon Consultant
Allergy & Clinical Immunology


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T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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