Clinical Case Database / Category: Clinical Care
Nutrition in cancer patients
Publication details
Dr Mahmoud Ali Zohree Ali, Dr Paul Ross
Foundation Years Journal, volume 6, issue 9, p.46 (123Doc Education, London, October 2012)
Abstract
Patients with cancer suffer a variety of symptoms. Cancer-associated malnutrition is one of the most common symptoms encountered. It can result from the systemic and local effects of a tumour, the host response to the tumour or advanced anticancer therapies (surgery, chemotherapy, radiotherapy, biological immunotherapy and hormonal treatment). Cachexia often occurs in advanced cancer. It is a multifactorial syndrome characterized by anorexia accompanied by generalized host tissue wasting, skeletal muscle atrophy, immune dysfunction, and metabolic derangements. Cancer patients therefore have the double burden of fighting cancerous cells and finding ways of replacing damaged cells. Although cancer patients often have reduced food intake, alterations in metabolism and resting energy expenditure may also contribute to their nutritional status. Several agents produced in response to the tumour, such as pro-inflammatory cytokines and hormones, have been implicated in the pathogenesis of malnutrition and cachexia.
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Authors
Dr Mahmoud Ali Zohree Ali
Clinical Fellow Medical Oncology
Guys Hospital
Dr Paul Ross
Consultant Medical Oncology
Medical Oncology Department
Guys Hospital
References
1. European journal of nursing. The cause and consequences of cancerassociated malnutrition.Eric Van Cutsem, Jann Arends. 2005.
2. Zeman FJ: Nutrition and cancer. In: Zeman FJ: Clinical Nutrition and Dietetics. 2nd ed. New York, NY: Macmillan Pub . Co, 1991, pp 571-98.
3. Albrecht JT, Canada TW: Cachexia and anorexia in malignancy. Hematol Oncol Clin North Am 10 (4): 791-800, 1996.
4. http://www.cancer.gov/cancertopics/pdq/supportivecare/nutrition/HealthProfessional/Page4#Section_50
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