Clinical Case Database / Category: Patient Management

Orbital apex syndrome secondary to herpes zoster ophthalmicus

Publication details

Dr F Angela Knox MRCOphth, Dr Martin Murphy FRCOphth, Dr D Patel MRCOphth
Foundation Years Journal, volume 4, issue 6, p.24 (123Doc Education, London, June 2010)


We report a case of herpes zoster ophthalmicus complicated by orbital apex syndrome. The clinical course and treatment of the patient is detailed with discussion of hypothesised pathogenesis in the published literature. This case highlights the possible associated ocular complication of herpes zoster ophthalmicus.

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Dr F Angela Knox MRCOphth

Department of Ophthalmology
Royal Victoria Hospital

Dr Martin Murphy FRCOphth

Department of Ophthalmology
Royal Victoria Hospital

Dr D Patel MRCOphth

Department of Ophthalmology
Royal Victoria Hospital
Grosvenor Road
Belfast BT12 6BA


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11. Liu YL, Shiau SC, Lin CP. (2005) Herpes zoster ophthalmicus complicated with meningoencephalitis and orbital apex syndrome: a case report. Changhua J Med. 10:27–30.
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13. Kattah JC, Kennerdell JS. (1978) Orbital apex syndrome secondary to herpes zoster ophthalmicus. Am J Ophthalmol, 85:378–382.


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About the Clinical Cases Database

T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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