Clinical Case Database / Category: Patient Management

Orbital apex syndrome secondary to herpes zoster ophthalmicus

Publication details

Dr F Angela Knox MRCOphth, Dr Martin Murphy FRCOphth, Dr D Patel MRCOphth
Foundation Years Journal, volume 4, issue 6, p.24 (123Doc Education, London, June 2010)

Abstract

We report a case of herpes zoster ophthalmicus complicated by orbital apex syndrome. The clinical course and treatment of the patient is detailed with discussion of hypothesised pathogenesis in the published literature. This case highlights the possible associated ocular complication of herpes zoster ophthalmicus.

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Authors

Dr F Angela Knox MRCOphth

Department of Ophthalmology
Royal Victoria Hospital
Belfast

Dr Martin Murphy FRCOphth

Department of Ophthalmology
Royal Victoria Hospital
Belfast

Dr D Patel MRCOphth

Department of Ophthalmology
Royal Victoria Hospital
Grosvenor Road
Belfast BT12 6BA
dimple.patel@doctors.org.uk

References

1. Marsh RJ, Dulley B, Kelly V. (1977) External ocular motor nerve palsies in ophthalmic zoster: a review. British Journal of Ophthalmology, 7(61):677–682.
2. Archambault P, Wise JS, Rosen J, Polomeno RC, Auger N. (1988) Herpes zoster ophthalmoplegia. Journal of Clinical Neuro-Ophthalmology, 8(3):185–191.
3. Chang-Godinich A, Lee AG, Brazis PW, Liesegang TJ, Jones DB. (1997) Complete ophthalmoplegia after zoster ophthalmicus. Journal Of Neuro-Ophthalmology 17(4):262–265.
4. Tayson DeLengocky, Christina M. (2008) Complete Ophthalmoplegia With Pupillary Involvement as an Initial Clinical Presentation of Herpes Zoster Ophthalmicus. J Am Osteo Assoc, 108(10):615–621.
5. Cope S, Jones AT. (1954) Hemiplegia complicating ophthalmic zoster. Lancet 2:898–899.
6. Gordon IRS, Tucker JD. (1945) Lesions of the central nervous system in herpes zoster. Journal of Neurology and Psychiatry. 8:40–46.
7. Krumholz S, Luihan JA. (1945) Encephalitis associated with herpes zoster. Archives of Neurology and Psychiatry, 53:59–67.
8. Bourke RD, Pyle J. (1994) Herpes zoster ophthalmicus and the orbital apex syndrome. Aust NZ J Ophthalmo, 22(1):77–80.
9. Yong VKY, Yip CC, Yong VSH. (2001) Herpes zoster ophthalmicus and the superior orbital fissure syndrome. Singapore Med J. 42(10):485–486.
10. Garg RK, Kar AM, Jain AK. (1992) Hepres zoster ophthalmicus with complete external ophthalmoplegia. J Assoc Physicians India. 40:496–497.
11. Liu YL, Shiau SC, Lin CP. (2005) Herpes zoster ophthalmicus complicated with meningoencephalitis and orbital apex syndrome: a case report. Changhua J Med. 10:27–30.
12. Dhingra S, Williams G, Pearson A. (2008) Severe, Permanent Orbital Disease in herpes zoster ophthalmicus. Orbit. 27(4):325–327.
13. Kattah JC, Kennerdell JS. (1978) Orbital apex syndrome secondary to herpes zoster ophthalmicus. Am J Ophthalmol, 85:378–382.

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About the Clinical Cases Database

T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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