Clinical Case Database / Category: Patient Management
Treating Crohn's disease with diet and antifungals
Foundation Years Journal, volume 7, issue 8, p.28 (123Doc Education, London, August 2013)
The case of a patient with Crohn's disease is reported where treatment with dietary measures as well as intraluminal anti-fungal medication for underlying changes to the gut flora resulted in clinical and radiological remission. The potential role of the microbiome in particular the gut microflora is discussed in the context of inflammatory bowel disease. In particular, it is speculated that due to the high burden of antibiotic use both in medical practice and through exposure to food produced on farms where routine use of antibiotics enter the food chain, fungal type dysbiosis may compound the symptoms and progression of inflammatory bowel diseases such as Crohn's disease. It follows that treatment with simple dietary protocols and antifungals may in a subset of patients alter the clinical course and natural history of the condition.
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About the Clinical Cases Database
The Foundation Years Clinical Cases Database is a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.
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