Clinical Case Database / Category: Patient Management

Tuberous sclerosis associated renal cell carcinoma

Publication details

Miss Gemma McKenzie, Professor Marek Miller, FRCS
Foundation Years Journal, volume 8, issue 10, p.42 (123Doc Education, London, November 2014)


We present an interesting case of a 20 year old male with Tuberous Sclerosis, a rare autosomal dominant condition characterised by multi-organ hamartomas. This condition is expressed with huge variability across patients, with multiple extra-hamartomatous manifestations including; seizures, learning difficulties, behavioural problems, skin conditions and other multi-organ complications. In addition to the well-documented hamartomas, these patients can present with malignant tumours and here we discuss the unfortunate case of a 20 year old male with an incidental finding of a 65mm renal cell carcinoma picked up on routine Computed Tomography (CT) imaging.

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Miss Gemma McKenzie (Corresponding author)

Urology SpR Northampton Hospital, 6 Grove Works,
72 Clare Street, Northampton, NN1 3LS

Professor Marek Miller, FRCS

Consultant Urologist, 6 Grove Works,
72 Clare Street, Northampton, NN1 3LS


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T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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