Clinical Case Database / Category: Patient Management

Investigations and management of recurrent miscarriages

Publication details

Rekha Remadevi, MBChB, MRCOG, Fadi Alfhaily, MBChB, MSc, DFFP, MRCOG, Jonathan Evans-Jones, MBBS FRCOG
Foundation Years Journal, volume 5, issue 5, p.66 (123Doc Education, London, June 2011)


Recurrent miscarriage is defined as the loss of three or more pregnancies. It is a heterogeneous condition that has many possible causes; more than one contributory factor may underlie the recurrent pregnancy losses. Recurrent miscarriage affects 1% of couples who are trying to achieve a successful pregnancy. Because the incidence is higher than expected of chance alone (0.34%), a proportion of couples with recurrent miscarriage have a persistent underlying cause for their pregnancy losses.

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Rekha Remadevi, MBChB, MRCOG

Specialty trainee in Obstetrics and Gynaecology, Colchester University Hospital
NHS Foundation Trust

Fadi Alfhaily, MBChB, MSc, DFFP, MRCOG

Consultant Obstetrician and Gynaecologist,
Colchester University Hospital
NHS Foundation Trust

Jonathan Evans-Jones, MBBS FRCOG

Consultant Obstetrician and Gynaecologist,
Colchester University Hospital
NHS Foundation Trust


1. Evidence-based guidelines for the investigation and medical treatment of recurrent miscarriage Eric Jauniaux, Roy G. Farquharson, Ole B. Christiansen and Niek Exalto On behalf of ESHRE Special Interest Group for Early Pregnancy (SIGEP).
2. RCOG green top guideline: Investigation and treatment of couples with recurrent miscarriage
3. Recent advances in Obstetrics and Gynaecology 24th edition.
4. Al-Fozan H. and Tulandi T. (2004a) Incidence and etiology of recurrent pregnancy loss. Uptodate online, volume 13.2, May 2005.
5. The Dutch Society of Obstetrics and Gynaecology (NVOG). Guideline recurrent miscarriage. The Netherlands: The Dutch Society of Obstetrics and Gynaecology (NVOG); 2007 Aug 06. 20 p. [67 references]. The National Guideline Clearinghouse: Techniques


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T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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