Clinical Case Database / Category: Patient Management

The many faces of sarcoidosis

Publication details

Ruwani Rupesinghe, Maria Trawinska, Simon P Hart
Foundation Years Journal, volume 9, issue 4, p.56 (123Doc Education, London, April 2015)

Abstract

Sarcoidosis is a multisystem inflammatory disease of unknown aetiology. Its incidence is difficult to determine due to significant heterogeneity in disease presentation and severity among different ethnic and racial groups and geographical variation. We present a case that illustrates biochemical, radiological, and pathological abnormalities in sarcoidosis. We discuss complications and evidence for treatment in sarcoidosis.

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Authors

Ruwani Rupesinghe

Castle Hill Hospital
Hull and East Yorkshire Hospitals NHS Trust
Cottingham, UK, HU16 5JQ
ruwani.rupesinghe@hey.nhs.uk

Maria Trawinska

Castle Hill Hospital
Hull and East Yorkshire Hospitals NHS Trust
Cottingham, UK, HU16 5JQ
maria.trawinska@hey.nhs.uk

Simon P Hart (Corresponding author)

Academic Respiratory Medicine
Castle Hill Hospital
Hull York Medical School
Hull and East Yorkshire Hospitals NHS Trust
Cottingham, UK, HU16 5JQ
s.hart@hull.ac.uk

References

1. Bradley B, Branley HM, Egan JJ, Greaves MS, Hansell DM, Harrison NK, Hirani N, Hubbard R, Lake F, Millar AB, Wallace WA, Wells AU, Whyte MK, Wilsher ML. Interstitial lung disease guideline: the British Thoracic Society in collaboration with the Thoracic Society of Australia and New Zealand and the Irish Thoracic Society. Thorax. 2008 Sep;63 Suppl 5:v1-58.
2. Cox CE, Davis-Allen A, Judson MA. Sarcoidosis. Med Clin North Am. 2005; 89:817-28
3. Krell W, Bourbonnais JM, Kapoor R, Samavati L. Effect of smoking and gender on pulmonary function and clinical features in sarcoidosis. Lung. 2012 ;190:529-36
4. Conron M, Young C, Beynon HLC. Calcium metabolism in sarcoidosis and its clinical implications. Rheumatology 2000; 39:707-713
5. Grutters JC, van den Bosch JMM. Corticosteroid treatment in sarcoidosis. Eur Respir J 2006; 28:627-636
6. Gibson GJ et al. British Thoracic Society Sarcoidosis Study: effects of long term corticosteroid treatment. Thorax 1996; 51:238-247
7. Paramothayan S, Jones PW. Corticosteroid therapy in pulmonary sarcoidosis: a systematic review. JAMA 2002; 287:1301-1307
8. Gottlieb JE, Israel HL, Steiner RM, Triolo J, Patrick H. Outcome in sarcoidosis: the relationship of relapse to corticosteroid therapy. Chest 1997; 111:623-31
9. Callejas-Rubio J, Lopez-Perez L, Ortego-Centeno N. Tumour necrosis factor-alpha inhibitor treatment for sarcoidosis. Ther Clin Manag. 2008; 4:1305-1313
10. Baughman RP, Drent M, Kavuru M, Judson MA, Costabel U, du Bois R, Albera C, Brutsche M, Davis G, Donohue JF, Müller-Quernheim J, Schlenker-Herceg R, Flavin S, Lo KH, Oemar B, Barnathan ES; Sarcoidosis Investigators. Infliximab therapy in patients with chronic sarcoidosis and pulmonary involvement. Am J Respir Crit Care Med. 2006;174:795-802
11. Padilla ML, Schilero GJ, Teirstein AS. Sarcoidosis and transplantation. Sarcoidosis Vasc Diffuse Lung Dis. 1997;14:16-22

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About the Clinical Cases Database

T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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