Clinical Case Database / Category: Patient Management

Pancytopenia: a case of hairy cell leukaemia

Publication details

Dr Isabella S L Lo, Dr Alison E Milne
Foundation Years Journal, volume 9, issue 3, p.64 (123Doc Education, London, March 2015)

Abstract

Pancytopenia is a common presentation to our day-to-day clinical practice. The causes of pancytopenia are diverse and severe pancytopenia can be life threatening therefore warrant urgent assessment and treatment. In this article, we described a case of pancytopenia caused by a rare form of leukaemia, hairy cell leukaemia, and illustrated a step-to-step approach leading to the diagnosis.

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Authors

Dr Isabella S L Lo

Haematology Department
North Hampshire Hospital, Basingstoke, Hampshire, RG24 9NA
isabella.lo@hhft.nhs.uk

Dr Alison E Milne (Corresponding author)

Haematology Department
North Hampshire Hospital, Basingstoke, Hampshire, RG24 9NA
alison.milne@hhft.nhs.uk

References

1. Jones G, Parry-Jones N, Wilkins B, Else M, Catovsky D. Revised guidelines for the diagnosis and management of hairy cell leukaemia and hairy cell leukaemia variant*. British Journal of Haematology. 2012;156(2):186-95.
2. Tiacci E, Trifonov V, Schiavoni G, Holmes A, Kern W, Martelli MP, et al. BRAF Mutations in Hairy-Cell Leukemia. New England Journal of Medicine. 2011;364(24):2305-15.

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Conflict Of Interest

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When reporting experiments on human subjects, the Journal requires authors to indicate whether the procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the HelsinkiDeclaration of 1975, as revised in 2008.

About the Clinical Cases Database

T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

The database is fully searchable, or can be browsed by medical specialty. Abstracts can be read free of charge, however a subscription is required in order to read the complete cases.