Clinical Case Database / Category: Patient Management

Hypoglycaemia in a non-diabetic: vague non-specific symptoms but a serious underlying pathology

Publication details

Dr Roselle Herring, Dr Simon Aylwin, Dr Gordon Caldwell, Dr Julia Prague
Foundation Years Journal, volume 4, issue 9, p.30 (123Doc Education, London, December 2010)


We describe a case of severe symptomatic hypoglycaemia in a nondiabetic patient presenting to A&E. The associated discussion outlines the management of hypoglycaemia and explores the differential diagnosis, investigation and localisation of a potential insulinoma.

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Dr Roselle Herring

Specialist Registrar in Diabetes and Endocrinology
West Sussex NHS Trust
Worthing Hospital

Dr Simon Aylwin

Consultant Endocrinologist
King's College NHS Foundation Trust
King's College Hospital

Dr Gordon Caldwell

Consultant Diabetologist
West Sussex NHS Trust
Worthing Hospital

Dr Julia Prague

Foundation Year Trainee
West Sussex NHS Trust
Worthing Hospital
Lyndhurst Road
West Sussex
BN11 2DH


1. Gadsby R (date unknown) Hypoglycaemia: diagnosis and management. BMJ Learning. Accessed online:
2. Turner H, Wass, JAH. (2001) Oxford Handbook of Endocrinology and Diabetes. Oxford University Press.
3. Rostambeigi N, Thompson GB (2009) What should be done in an operating room when an insulinoma cannot be found? Clinical Endocrinology, 70: 512–515.
4. Advanced Trauma Life Support Course Manual (date unknown) Royal College of Surgeons, UK.


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About the Clinical Cases Database

T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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